After learning about Sherlock Holmes, Humphrey the classroom hamster follows clues to try and discover why Mrs. Brisbane is gone and Mr. E., a fun but not very educational substitute, is taking her place in Room 26 at Longfellow School.

A.J. and his friends think that Ms. Todd is the strangest substitute teacher in the world, and they decide to investigate her.

When her substitute teacher realizes she is struggling in math, Judy is sent to a math tutor at the local college and soon is completely into the spirit of college life.

In a series of letters a student laments the absence of her teacher and daily routine, but she soon realizes there are benefits to mixing things up, and that perhaps having a substitue teacher is not so bad afterall.

"When Milton Worthy learns his classroom's pet ferret is the evil mastermind behind a dastardly plot for world domination, it's more than just about any kid could handle. But then not every kid is the son of a member of the super-secret, super-awesome Society of Substitutes! Now it's up to Milton and his substitute teacher mom to save Beacher Elementary School before time runs out." -- Page [4] of cover.

When Mrs. Green is out sick, her students worry that their substitute teacher might be a giant monster who will hurl them into outer space.

Sam, Lucy, and Antonio have a new substitute teacher, who happens to be the great-great-grandson of Orson Eerie, the evil scientist whose spirit possesses and infects their elementary school--and the friends are afraid he may be trying to bring Orson back to life.

Nikki and Deja are scared about what the bad kids in their class will do now that Ms. Shelby-Ortiz is gone and Room Ten has a substitute teacher. However, they struggle with figuring out if tattling on their classmates is the right thing to do, or if there is some better way to help keep the peace.

Three seventh-graders at Ravens Pass Middle School cheat on a math test and think they have gotten away with it--until a very strange substitute teacher starts treating them in an ominous manner.

"It's just another ordinary day at Horace Green Prep School, and the students think they're getting just another ordinary substitute teacher. Instead, Dewey Finn, a washed-up musician with dreams of greatness, whisks them away on a totally rocking adventure. After Dewey hears the kids practicing in music class, he discovers how talented they are and realizes he has another chance at his greatest dream: winning the Battle of the Bands. But when the...