When they are selected to read speeches at their elementary school graduation, an unlikely friendship develops between two sixth-graders, one popular and one a misfit, who are facing family problems and health issues.
When Noah draws with the special pencil from the Zooniverse book, the picture comes to life and Noah and Blue end up with a tigerdillo, a combination of a tiger and an armadillo, on their camping trip.
This time, Noah and Blue mash up an inky octopus with a marmoset monkey, creating Ockie. Things go wrong when the rambunctious and many-limbed Ockie gets loose in their school.
Noah and Blue design an eight-legged dinosaur by crossing a T. rex with a tiny spider called spidersaurus--or Spidey. However, Spidey gets loose and starts spinning webs in their school.